This medication may interfere with certain medical/lab tests (such as brain scan for Parkinson's disease, urine drug screening tests), possibly causing false test results. What Are the Side Effects of Promethazine DM? Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? Erika Prouty, PharmD, is a professional community pharmacist who aids patients in medication management and pharmacy services in North Adams, Massachusetts. Promethazine DM generally takes around 30 minutes to start reducing cough symptoms. Dextromethorphan is a. Codeine and dextromethorphan likely stop coughs by decreasing activity in the area of the brain responsible for producing coughs. Talk to your doctor if you are using marijuana (cannabis). promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. These cookies ensure basic functionalities and security features of the website, anonymously. Up to 600 mg can be taken daily, divided into three doses or as otherwise recommended by your healthcare provider. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. CNS: Disturbed coordination, tremor, irritability, insomnia, visual disturbances, weakness, nervousness, convulsions, headache, euphoria, and dysphoria. Keep all regular medical and laboratory appointments. Taking certain MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. 19,468 people who take Bromfed-dm and Promethazine dm are studied. This cookie is set by GDPR Cookie Consent plugin. Do not start, stop, or change the dosage of any medicines without your doctor's approval. In young children, this medication may cause agitation/excitement instead of drowsiness. Additional Content Provided and Reviewed by IBM Micromedex. Does Bromphen PSE DM contain acetaminophen? If you are taking this medication for allergy or hay fever symptoms, take it regularly in order to get the most benefit from it. They are not to be used for the chronic cough that occurs with smoking, asthma, or emphysema or when there is an unusually large amount of mucus or phlegm (pronounced flem) with the cough. Also, do not split extended-release tablets unless they have a score line and your doctor or pharmacist tells you to do so. Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Cough/cold combination products contain more than one ingredient. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Do not use a household spoon. This means that any drug that impacts CYP2D6 enzymes might not be cleared as quickly. In: StatPearls. Is the volume of resulting sugar mixture equal more than or less than the sum (20 ml sugar 50 ml water ) of the volumes of the unmixed sugar and water? A very serious allergic reaction to this drug is rare. Does Bromphen-PSE-DM-Acetaminophen Syrup interact with other medications? . Dosage Available as pill and suppository: 12.5 mg, 25 mg or 50 mg Available as an oral solution: 6.25 mg/5 mL Available as a solution for injection: 25 mg/mL or 50 mg/mL; Used to Treat Allergic reactions and to sedate patients before and after surgery and during labor, to prevent and control nausea and vomiting; The extended release version of Mucinex DM lasts up to 12 hours. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. Hypersensitivity to any of the ingredients. Swallow the whole or split tablet without crushing or chewing. Examples of other cough medicines are: This list includes drugs also prescribed for the targeted condition(s). Brompheniramine is an antihistamine. The toxic dose of pseudoephedrine should be less than that of ephedrine, which is estimated to be 50 mg/kg. Doing so can release all of the drug at once, increasing the risk of side effects. This document does not contain all possible drug interactions. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 19,468 people who take Bromfed-dm and Promethazine dm, and is updated regularly. . Benzonatate is a prescription, non-narcotic antitussive medication that numbs the airways, the air sacs (alveoli) in the lungs, and the lining of the lungs (pleura). Promethazine Facts. Teimoory M, Arefi M, Behnoush B, Bastani B. Drink plenty of fluids when you use this medication unless otherwise directed by your doctor. Before taking this product, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Anticholinergic effects may be noted. Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. You may report side effects to Health Canada at 1-866-234-2345. Dizziness, drowsiness, and confusion can increase the risk of falling. Bromphen is used to treat runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu. Sympathomimetic may reduce the effects of antihypertensive drugs. Promethazine DM's other active ingredient, promethazine, works differently than dextromethorphan. Examples of CYP2D6 inducers are: Promethazine DM also has other interactions that are unrelated to any enzyme. Some brands of this product may contain sugar, alcohol, or aspartame. Bromfed DM Cough Syrup has a butterscotch flavor and is a clear, light pink syrup. Does Bromphen-PSE-DM-Acetaminophen Syrup interact with other drugs you are taking? Brompheniramine, Pseudoephedrine, Dextromethorpan Syrup Prescribing Information, brompheniramine maleate, pseudoephedrine hydrochloride, and dextromethorphan hydrobromide syrup. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. If any of these effects last or get worse, notify your doctor or pharmacist promptly. The Food and Drug Administration (FDA) approved Promethazine DM for the temporary relief of the following: Promethazine DM is a medication that should only be taken under a healthcare provider's direct guidance and recommendation. What Other Medications Interact With Promethazine DM? Brompheniramine is well absorbed from the gastrointestinal tract, with peak plasma concentration after single, oral dose of 4 mg reached in 5 hours; urinary excretion is the major route of elimination, mostly as products of biodegradation; the liver is assumed to be the main site of metabolic transformation. If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. You and your healthcare provider must check your progress at regular visits. What are the physical state of oxygen at room temperature? Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. It is often used in cough. 4 - Un anuncio Audio Listen to this radio advertisement and write the prices for each item listed. Animal reproduction studies have not been conducted with Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup. In addition to taking this medication, try to get lots of rest, stay hydrated, eat a healthy diet based on your individual needs, and consume adequate fiber. If you have any questions, consult your pharmacist. We study millions of patients and 5,000 more each day. . You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine). If you plan to travel with Promethazine DM, get familiar with your final destination's regulations. Other adverse reactions may include: Dermatologic: Urticaria, drug rash, photosensitivity, pruritus. 3. It's known as a drowsy (sedating) antihistamine, so it's more likely to make you feel sleepy than other antihistamines. Brand names include Bromfed, Dimetapp, Bromfenex, Dimetane, BPN, Lodrane. Serious side effects include confusion; extreme drowsiness/difficulty waking; noisy, slow, or shallow, breathing; fast or irregular . The sooner that overdose symptoms are treated, the less likely complications will occur. 2010;88(5):643-651. doi:10.1038/clpt.2010.137. C 16H 19BrN 2C 4H 4O 4 M.W. 2005 - 2023 WebMD LLC. Can you take bromfed DM if you have asthma? Verywell Health's drug information is meant for educational purposes only and is not intended to replace medical advice, diagnosis, or treatment from a healthcare provider. This medication may pass into breast milk and may have undesirable effects on a nursing infant. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Ask your pharmacist about using those products safely. For relief of coughs and upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold. Our phase IV clinical studies alone cannot establish cause-effect relationship. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. Follow your healthcare provider's orders or the directions on the label. If you notice other effects not listed above, contact your doctor or pharmacist. Drug class: Upper respiratory combinations. WebMD does not provide medical advice, diagnosis or treatment. Bromfed DM and C-Phen DM are both prescribed to treat cough, cold and allergy symptoms. If stomach upset occurs, it may help to take this medication with food or milk. Ask your doctor or pharmacist for more details about using your product safely.These products do not cure or shorten the length of the common cold and may cause serious side effects. Things to remember when you fill your prescription. Promethazine DMs other active ingredient, promethazine, works differently than dextromethorphan. . Antihistamines should not be used to treat lower respiratory tract conditions including asthma. In the US - Call your doctor for medical advice about side effects. (473ml) - NDC 62135-302-47 - Label. Keep all medications away from children and pets. Promethazine DM (dextromethorphan and promethazine) is a combination cough syrup that treats common cold and allergy symptoms. Brompheniramine also has anticholinergic (drying) and sedative effects. Some products have ingredients that could affect your heart rate or blood pressure. . If your doctor has prescribed this medication, take it as directed. Codeine is a narcotic cough suppressant. Is there a way I can get help paying for it? You can opt-out at any time. Antihistamines may diminish mental alertness. only. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Acetaminophen is in many nonprescription and prescription medications (such as pain/fever drugs or cough-and-cold products). CYP2D6 inducers decrease the amount of certain drugs in the body. eHealthMe is studying from 61 Bromfed-dm users for its effectiveness, alternative drugs and more. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. We also use third-party cookies that help us analyze and understand how you use this website. Before bed. System: Urinary frequency, difficult urination. Avoid alcoholic beverages. 435.31, Brompheniramine Maleate, USP()-2- p-Bromo--2-(dimethylamino)ethylbenzylpyridine maleate (1:1), C 10H 15NOHCl M.W. We compare the side effects and drug effectiveness of Bromfed-dm and Promethazine. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Dextromethorphan is a cough suppressant that affects a certain part of the brain (cough center), reducing the urge to cough. Bromfed-dm has active ingredients of brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride. Copyright 2023 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. RxList does not provide medical advice, diagnosis or treatment. Make a copy of your Promethazine DM prescription, and if possible, keep your medication in its original container from your pharmacy with your name on the label. Drink all of the liquid right away. Selected from data included with permission and copyrighted by First Databank, Inc. These medicines may decrease how well CYP2D6 enzymes can clear other medications from the body. Ask your pharmacist or medical provider about the best ways to dispose of this medicine. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Discuss with your healthcare provider if you are or plan to become pregnant, and weigh the benefits and risks of taking Promethazine DM during your pregnancy. 2 mg. Pseudoephedrine Hydrochloride, USP . How much does Promethazine DM cost? Betahistine is a vasodilator, a modest H 1 histamine agonist, and a powerful H 3 histamine receptor antagonist. The following information includes only the average doses of this medicine. You also have the option to opt-out of these cookies. Clinical studies of Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Especially in infants and small children, antihistamines in overdosage may cause hallucinations, convulsions, and death. Hi, I am intersted in a medication (s) that have the same effect as Bromfed DM read more. It should be given to a pregnant woman only if clearly needed. Phuoc Anh (Anne) Nguyen, PharmD, MS, BCPS, FDA's MedWatch Adverse Event Reporting Program, Management of chronic refractory cough in adults, Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity, Assessment of activity levels for CYP2D6*1, CYP2D6*2, and CYP2D6*41 genes by population pharmacokinetics of dextromethorphan, Upper respiratory symptoms associated with allergies or a cold. Bromfed DM will not treat a cough that is caused by smoking, asthma, or emphysema. generic drugs or brand names) are also considered. Other medicines that impact how CYP2D6 works may also change how well Promethazine DM works. Take your next dose at the regular time. . It's okay if you miss a dose of Promethazine DM. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Adults and pediatric patients 12 years of age and over: 10 mL (2 teaspoonfuls) every 4 hours. Dextromethorphan acts centrally to elevate the threshold for coughing. Take this medication by mouth with or without food or as directed by your doctor. Properly discard this product when it is expired or no longer needed. Number of reports submitted per year: Drugs being compared in this study: Promethazine DM should not be consumed within 14 days of taking a drug in the monoamine oxidase inhibitor (MAOI) drug class. Discard all unused and expired drugs but do not pour them down the drain or toilet. Overdose: What Happens If I Take Too Much Promethazine DM? Answer (1 of 10): Ok those are better than I was told. Generally, dosing will vary between every four to six hours by mouth, as needed, while youre feeling sick. Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, hallucinations), ringing in the ears, shaking (tremors), trouble urinating, weakness, easy bruising/bleeding, fast/slow/irregular heartbeat, seizure. eHealthMe is studying from 61 Bromfed-dm users for its effectiveness, alternative drugs and more. A dangerous drug interaction could occur. US residents can call their local poison control center at 1-800-222-1222. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Select a condition to view a list of medication options. What should I know regarding pregnancy, nursing and administering BROMPHENIRAMINE-PSEUDOEPHED-DM to children or the elderly? Pseudoeph-Bromphen-Dm Interactions. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Dextromethorphan can make its way into breast milk. Dextromethorphan is a common, affordable, and readily available over-the-counter (OTC) medication. generic drugs or brand names) are also considered. This medication can dry up and thicken mucus in your lungs, making it more difficult to breathe and clear your lungs. Respiratory System: Tightness of chest and wheezing, shortness of breath. Generic name: BROMPHENIRAMINE MALEATE 2mg in 5mL, PSEUDOEPHEDRINE HYDROCHLORIDE 30mg in 5mL, DEXTROMETHORPHAN HYDROBROMIDE 10mg in 5mL. Taking too much acetaminophen may cause serious (possibly fatal) liver disease. How Can I Stay Healthy While Taking Promethazine DM? These cookies will be stored in your browser only with your consent. . Ask your doctor when to start or stop taking this medication. Drowsiness, dizziness, headache, blurred vision, upset stomach, nausea, constipation, or dry mouth/nose/throat may occur. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. "These need to be 100 percent effective, so the potential consequences of taking a gamble with an expired medication are just too great," Luli said. This medication may pass into breast milk. If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. The amount of medicine you take depends on the strength of the medicine. Ask your doctor when to start or stop taking this medication. Does bromphen/pseudo/dextro hbr syrup have alcohol? Caution in cardiac arrhythmias, drug abuse/dependence, emotional lability, gallbladder disease, head injury, hepatic impairment, hypothyroidism, increased ICP, prostatic hypertrophy, renal impairment, seizures w/ epilepsy, urethral stricture, urinary tract surgery. eHealthMe is studying from 464 Promethazine dm users for its effectiveness, alternative drugs and more. promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. Discuss the risks and benefits with your doctor. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals.